HCID 6417976, compound → HCID 6417966, compound

Participants

Reaction Steps

500 mg (1.65 mmol) of 2,6-bis(3-chloropyridazin-6-yl)-pyridine 32 and 17.5 mg (0.08 mmol) of palladium-on-charcoal are dissolved in 50 ml of ethanol. The mixture is stirred at ambient temperature under a hydrogen pressure for 24 hours. The solution is filtered, evaporated under reduced pressure, and then chromatographed on silica gel (eluent: ethyl acetate/petroleum ether: 8/2). The 2,6-bis(3′-pyridazinyl)pyridine 37 is isolated with a yield of 89%.

Provenance & Evidence