HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxyisobutyric acid → 2-(5-(3-Amino-6-bromo-5-(trifluoromethyl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxyisobutyric acid | HCID 11671 | — |
| Reactant | 3-Amino-6-bromo-5-(trifluoromethyl)picolinohydrazide | HCID 86729595 | — |
| Product | 2-(5-(3-Amino-6-bromo-5-(trifluoromethyl)pyridin-2-yl)-1,3,4-oxadiazol-2-yl)propan-2-ol | HCID 71515755 | — |
Reaction Steps
The title compound was prepared from 3-amino-6-bromo-5-(trifluoromethyl)picolinohydrazide (Intermediate H) and 2-hydroxy-2-methylpropanoic acid analogously to Example 10 (leave out step 4);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034879B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-bdf73d660b6d4e42a6e45c47867e973f |
| Source note | uspto-grants-2015_05 |