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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574459Generated: October 29, 2026

Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → 8-chloro-2,3,4,5-tetrahydro-2-methyl-5-(3-(pyrrolidin-1-yl)propyl)-1H-pyrido[4,3-b]indole

https://huagongshe.com/reaction/574459

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine, (4-chlorophenyl)-, hydrochloride (1:1)HCID 71600—
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant1-(3-Bromopropyl)pyrrolidineHCID 13034044—
SolventTriethylamineHCID 8471—
Product8-chloro-2,3,4,5-tetrahydro-2-methyl-5-(3-(pyrrolidin-1-yl)propyl)-1H-pyrido[4,3-b]indoleHCID 57875948—

Reaction Steps

The title compound is prepared by following Method 8 by using 1-(3-bromopropyl)pyrrolidine, 4-chlorophenylhydrazine hydrochloride, triethylamine and N-methyl-4-piperidone

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034880B2
Source datasetuspto-grants-2015_05
ORD IDord-a6762ace96424a50938045d608bbe82f
Source noteuspto-grants-2015_05