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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574701Generated: October 26, 2026

3-(5-methyl-1H-imidazol-1-yl)propan-1-amine → 6-ethyl-3-[3-(5-methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2,3-dihydro-thieno[2,3-d]pyrimidin-4(1H)-one

https://huagongshe.com/reaction/574701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(5-methyl-1H-imidazol-1-yl)propan-1-amineHCID 19429483—
ReactantMethyl 5-ethyl-2-isothiocyanatothiophene-3-carboxylateHCID 19620641—
Product6-ethyl-3-[3-(5-methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2,3-dihydro-thieno[2,3-d]pyrimidin-4(1H)-oneHCID 25099890—

Reaction Steps

The compound was synthesized starting from methyl 5-ethyl-2-isothiocyanatothiophene-3-carboxylate (0.1 g, 0.44 mmol) and 3-(5-methyl-1H-imidazol-1-yl)propan-1-amine (5) (0.06 g, 0.44 mmol) as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034907B2
Source datasetuspto-grants-2015_05
ORD IDord-ca151ab105744cb9809b6afc3f21f7da
Source noteuspto-grants-2015_05