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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574703Generated: October 31, 2026

Methyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylate → 5-ethyl-2,3-dihydro-6-methyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-2-thioxothieno[2,3-d]pyrimidin-4(1H)-one

https://huagongshe.com/reaction/574703

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylateHCID 4513532—
Reactant3-(5-methyl-1H-imidazol-1-yl)propan-1-amineHCID 19429483—
Product5-ethyl-2,3-dihydro-6-methyl-3-(3-(5-methyl-1H-imidazol-1-yl)propyl)-2-thioxothieno[2,3-d]pyrimidin-4(1H)-oneHCID 25100043—

Reaction Steps

The compound was synthesized starting from methyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylate (0.10 g, 0.41 mmol) and 3-(5-methyl-1H-imidazol-1-yl)propan-1-amine (5) (0.058 g, 0.41 mmol) as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034907B2
Source datasetuspto-grants-2015_05
ORD IDord-098252f37d7f4eacaf0d162f15d9ce3d
Source noteuspto-grants-2015_05