HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-isothiocyanato-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate → 3-[3-(4-methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2,3,6,7,8,9-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-isothiocyanato-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate | HCID 4512760 | — |
| Reactant | 3-(4-Methyl-1H-imidazol-1-yl)propan-1-amine | HCID 15034954 | — |
| Product | 3-[3-(4-methyl-1H-imidazol-1-yl)propyl]-2-thioxo-2,3,6,7,8,9-hexahydro[1]benzothieno[2,3-d]pyrimidin-4(1H)-one | HCID 25100204 | — |
Reaction Steps
The compound was synthesized starting from methyl 4,5,6,7-tetrahydro-2-isothiocyanatobenzo[b]thiophene-3-carboxylate (0.109 g. 0.43 mmol) and 3-(4-methyl-1H-imidazol-1-yl)propan-1-amine (9) (0.060 g, 0.43 mmol) as described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034907B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-1ed5223680fc4e36b20c16989557bbef |
| Source note | uspto-grants-2015_05 |