1H-Imidazole-1-propanamine → 5-ethyl-3-[3-(1H-imidazol-1-yl)propyl]-6-methyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3H)-one

HRID 574727Notes

Reaction equation

HRID 574727 reaction equation
[CH2:1]([C:3]1[C:4]([C:12]([O:14]C)=O)=[C:5]([N:9]=[C:10]=[S:11])[S:6][C:7]=1[CH3:8])[CH3:2].[N:16]1([CH2:21][CH2:22][CH2:23][NH2:24])[CH:20]=[CH:19][N:18]=[CH:17]1>>[CH2:1]([C:3]1[C:4]2[C:12](=[O:14])[N:24]([CH2:23][CH2:22][CH2:21][N:16]3[CH:20]=[CH:19][N:18]=[CH:17]3)[C:10](=[S:11])[NH:9][C:5]=2[S:6][C:7]=1[CH3:8])[CH3:2]

Participants

3

Reactant 2

HCID 787361H-Imidazole-1-propanamineHCID 4513532Methyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylate

Product 1

HCID 51844225-ethyl-3-[3-(1H-imidazol-1-yl)propyl]-6-methyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3H)-one

Procedure

The compound was synthesized starting from methyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylate (0.010 g. 0.04 mmol) and 3-(1H-imidazol-1-yl)propan-1-amine (0.005 g, 0.04 mmol) as described above.

Workup

  1. customThe compound was synthesized

Sources & evidence

ORD record
ord-6e26a87d3a844083b03da2640c7c93cd
Source dataset
uspto-grants-2015_05
Patent number
US09034907B2

Reaction notes

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