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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 574727Generated: October 31, 2026

1H-Imidazole-1-propanamine → 5-ethyl-3-[3-(1H-imidazol-1-yl)propyl]-6-methyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3H)-one

https://huagongshe.com/reaction/574727

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantMethyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylateHCID 4513532—
Product5-ethyl-3-[3-(1H-imidazol-1-yl)propyl]-6-methyl-2-sulfanylthieno[2,3-d]pyrimidin-4(3H)-oneHCID 5184422—

Reaction Steps

The compound was synthesized starting from methyl 4-ethyl-2-isothiocyanato-5-methylthiophene-3-carboxylate (0.010 g. 0.04 mmol) and 3-(1H-imidazol-1-yl)propan-1-amine (0.005 g, 0.04 mmol) as described above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09034907B2
Source datasetuspto-grants-2015_05
ORD IDord-6e26a87d3a844083b03da2640c7c93cd
Source noteuspto-grants-2015_05