Morpholine → HCID 46785855, compound

HRID 574814Notes

Reaction equation

HRID 574814 reaction equation
[NH:1]1[CH2:6][CH2:5]O[CH2:3][CH2:2]1.[O:7]1[CH2:12][CH2:11][C:10](=O)[CH2:9][CH2:8]1.O=C1CCC([NH:21][C:22](=[O:28])[O:23][C:24]([CH3:27])([CH3:26])[CH3:25])CC1>>[O:7]1[CH2:12][CH2:11][CH:10]([N:1]2[CH2:2][CH2:3][N:21]([C:22]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:28])[CH2:5][CH2:6]2)[CH2:9][CH2:8]1

Participants

4

Reactant 3

HCID 8083MorpholineHCID 121599Tetrahydro-4H-pyran-4-oneHCID 1512535tert-butyl N-(4-oxocyclohexyl)carbamate

Product 1

HCID 46785855HCID 46785855, compound

Procedure

The title compound was prepared by substituting tert-butyl piperazine-1-carboxylate for morpholine and dihydro-2H-pyran-4(3H)-one for tert-butyl 4-oxocyclohexylcarbamate in EXAMPLE 39A.

Sources & evidence

ORD record
ord-49dd1a123e7f4a8f93ce2fb608f55e84
Source dataset
uspto-grants-2015_05
Patent number
US09034875B2

Reaction notes

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