Chlorosuccinimide → HCID 67169326, compound

HRID 574979Notes

Reaction equation

HRID 574979 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([CH2:7][N:8]2[C:12]3=[N:13][CH:14]=[C:15]([S:17]([NH2:20])(=[O:19])=[O:18])[CH:16]=[C:11]3[CH:10]=[CH:9]2)[CH2:3][CH2:2]1.[Cl:21]N1C(=O)CCC1=O>CC#N>[Cl:21][C:10]1[C:11]2[C:12](=[N:13][CH:14]=[C:15]([S:17]([NH2:20])(=[O:18])=[O:19])[CH:16]=2)[N:8]([CH2:7][CH:4]2[CH2:5][CH2:6][O:1][CH2:2][CH2:3]2)[CH:9]=1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 67127242HCID 67127242, compound

Product 1

HCID 67169326HCID 67169326, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of EXAMPLE 388C (0.15 g) and N-chlorosuccinimide (0.081 g) in CH3CN (8 mL) was heated at 90° C. for 16 hours. The solvent was removed, and the residue was purified by flash column chromatography on silica to give the title compound.

Workup

  1. customThe solvent was removed
  2. customthe residue was purified by flash column chromatography on silica

Sources & evidence

ORD record
ord-1d37a76c9da24a1fa7c45cface6f581c
Source dataset
uspto-grants-2015_05
Patent number
US09034875B2

Reaction notes

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