HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one → HCID 86693198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one | HCID 58221634 | — |
| Reactant | 9-Bromo-8-fluoro-4,5-dihydro-[1]benzoxepino[5,4-d]thiazole-2-carboxamide | HCID 86693059 | — |
| Product | HCID 86693198 | HCID 86693198 | 30% |
Reaction Steps
Similar to as described in General Procedure G, 9-bromo-8-fluoro-4,5-dihydrobenzo[2,3]oxepino[4,5-d]thiazole-2-carboxamide was reacted with 3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one (WO2009/158011A 1) to give the titled compound (34.8 mg, 30%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09034866B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-8aed2cbbb9b94ce2b6363c490e8eed23 |
| Source note | uspto-grants-2015_05 |