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HRID575287

反应详情

EQUATION

反应方程式

HRID 575287 的结构方程式

REACTANTS

反应物

2
结构：C#C[C@]1(O)CCN(C)C1=O
HCID86693296

未命名化合物

结构：NC(=O)c1nc2c(s1)C1CC(C1)c1ccc(Br)cc1-2
HCID86693314

未命名化合物

PRODUCTS

生成物

1
结构：CN1CC[C@@](O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C2CC3C2)C1=O
HCID86693313

未命名化合物

收率 59%

PROCEDURE

实验过程

Similar to as described in General Procedure G, 9-bromo-5,6-dihydro-4H-4,6-methanobenzo[6,7]cyclohepta[1,2-d]thiazole-2-carboxamide was reacted with (3R)-3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one to give the titled compound as an off-white solid (14.4 mg, 59%).