HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-tert-butyl 3-ureidopyrrolidine-1-carboxylate → (R)-1-(pyrrolidin-3-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-tert-butyl 3-ureidopyrrolidine-1-carboxylate | HCID 71113416 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | (R)-1-(pyrrolidin-3-yl)urea | HCID 59286189 | — |
Reaction Steps
(R)-tert-butyl 3-ureidopyrrolidine-1-carboxylate from step A was treated with HCl solution (in EtOAc, 30 mL) for 2 hours. The mixture was concentrated in vacuo to give the crude title compound. MS (m/z): 130 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434726B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-3adef84ce87b4695bba69b0c8b6f8979 |
| Source note | uspto-grants-2016_09 |