反应详情

To a suspension of N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide (0.5 g, 1.7 mmol) and potassium carbonate (0.28 g, 2.0 mmol) in acetone (10 mL) was added methyl iodide (0.12 mL, 2.0 mmol). The mixture was stirred at room temperature for 18 hours under atmosphere of nitrogen, then diluted with CH2Cl2 (20 mL), filtered through a plug of diatomaceous earth, rinsed with CH2Cl2 and evaporated to give product as a off-white solid. MS (m/z): 312 (M+H)+.

1. filtrationfiltered through a plug of diatomaceous earth
2. washrinsed with CH2Cl2
3. customevaporated
4. customto give product as a off-white solid