反应详情

A solution of 2-chloro-N-(3-(dibenzylamino)-2-hydroxypropyl)acetamide (1.0 g, 2.49 mmol), t-BuOK (0.39 g, 3.57 mmol) in t-BuOH (30 mL) was stirred at reflux overnight. After concentration, the residue was purified by column chromatography to give product as white solid.

1. temperatureat reflux overnight
2. concentrationAfter concentration
3. customthe residue was purified by column chromatography
4. customto give product as white solid