反应详情

To a solution of tert-butyl 3-oxopiperazine-1-carboxylate (1 g, 5 mmol) in DCM (15 mL) was added triethyloxonium tetrafluoroborate (2.9 g, 15 mmol). Stirred for 2 h and neutralized with sat. aq NaHCO3. Layers separated and aqueous layer extracted with DCM. Combined organic layers dried over Na2SO4, filtered, and concentrated to give the title compound, which was used directly without further purification.

1. customLayers separated
2. extractionaqueous layer extracted with DCM
3. dry with materialCombined organic layers dried over Na2SO4
4. filtrationfiltered
5. concentrationconcentrated