HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopiperidine hydrochloride, N1-BOC protected → HCID 59313133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopiperidine hydrochloride, N1-BOC protected | HCID 17750334 | — |
| Reactant | Methyl 4-amino-2-(methylsulfonyl)thiazole-5-carboxylate | HCID 59511825 | — |
| Product | HCID 59313133 | HCID 59313133 | — |
Reaction Steps
Analogously to the preparation of Example 49A, 335 mg (1.42 mmol) of tert-butyl 3-aminopiperidine-1-carboxylate hydrochloride and 3190 mg (2.84 mmol) of methyl 4-amino-2-(methylsulfonyl)-1,3-thiazole-5-carboxylate gave 158 mg (29% of theory) of the product as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434731B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-ba12e22605c74247aeb673a492175696 |
| Source note | uspto-grants-2016_09 |