Thionyl Chloride → Hydrochloric Acid

HRID 576979Notes

Reaction equation

HRID 576979 reaction equation
[Cl:1][C:2]1[N:3]([CH2:11]O)[N:4]=[C:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2.O=S(Cl)[Cl:15]>>[Cl:1][C:2]1[N:3]([CH2:11][Cl:15])[N:4]=[C:5]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6]2.[ClH:1]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 59589510(3-chloro-2H-indazol-2-yl)methanol

Product 2

HCID 313Hydrochloric AcidHCID 595894213-chloro-2-(chloromethyl)-2H-indazole

Procedure

(3-chloro-2H-indazol-2-yl)methanol was dissolved in SOCl2 (10 mL). The mixture was stirred at room temperature for 3 hours and evaporated to provide crude 3-chloro-2-(chloromethyl)-2H-indazole as a HCl salt.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-9993104bc27b407e9910ded7918038a1
Source dataset
uspto-grants-2015_05
Patent number
US09040538B2

Reaction notes

Loading…