反应详情

Analogously to the preparation of Example 38A, 150 mg (0.39 mmol) of tert-butyl 3-{[4-amino-5-(methoxycarbonyl)-1,3-thiazol-2-yl]amino}piperidine-1-carboxylate and 20 ml of hydrochloric acid in dioxane (4M) gave 130 mg (99% of theory) of the product as a solid.