HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 57728Generated: October 27, 2026
Ammonium Hydroxide → 3-(2-Benzyloxy-propionylamino)-3H-imidazole-4-carboxylic acid amide
https://huagongshe.com/reaction/57728
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 3-(2-Benzyloxy-propionylamino)-3H-imidazole-4-carboxylic acid methyl ester | HCID 89715195 | — |
| Product | 3-(2-Benzyloxy-propionylamino)-3H-imidazole-4-carboxylic acid amide | HCID 89717258 | 100% |
Reaction Steps
Compound 9 (8.2 g, 27 mmol) and ammonium hydroxide (100 mL) were mixed and heated to 60° C. for two hours. The reaction mixture was concentrated in vacuo to give compound 10 (7.8 g, 100% yield) as white solid. LC-MS: m/z 289 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09434733B2 |
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| Source dataset | uspto-grants-2016_09 |
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| ORD ID | ord-fdb8cfbb4f554818b646057d5349b883 |
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| Source note | uspto-grants-2016_09 |
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