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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577288Generated: October 29, 2026

Tert-butyl 3-oxopiperazine-1-carboxylate → HCID 66764735, compound

https://huagongshe.com/reaction/577288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 3-oxopiperazine-1-carboxylateHCID 3157178—
Reactant(5-bromo-2,3-difluorophenyl)methanolHCID 40427031—
ProductHCID 66764735HCID 66764735—

Reaction Steps

tert-butyl 4-(3,4-difluoro-5-(hydroxymethyl)phenyl)-3-oxopiperazine-1-carboxylate was prepared following the procedure in Example 27 (Step ii) using (5-bromo-2,3-difluorophenyl)methanol and tert-butyl 3-oxopiperazine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040545B2
Source datasetuspto-grants-2015_05
ORD IDord-315e90c16893400e9c9952cf238fc046
Source noteuspto-grants-2015_05