HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylic Acid → N-(4-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylic Acid | HCID 6581 | — |
| Reactant | 4-(2-Chloropyrimidin-4-ylthio)benzenamine 2-chloro-4-(4'-aminothiophenyl)pyrimidine | HCID 131731896 | — |
| Product | N-(4-(2-chloropyrimidin-4-ylthio)phenyl)acrylamide | HCID 86645568 | 56% |
Reaction Steps
In a procedure analogous to Example 15, reaction of 4-(2-chloropyrimidin-4-ylthio)benzenamine 2-chloro-4-(4′-aminothiophenyl)pyrimidine (800 mg, 3.37 mmol) and acrylic acid (463 μL, 6.74 mmol) furnished the product (550 mg, 56%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040549B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-1395b8747cca4448b5e21b7c656ebec2 |
| Source note | uspto-grants-2015_05 |