3-Bromopyridine → HCID 86706425, compound

Participants

Reaction Steps

The title compound was prepared in the same procedure as described in Example 3-(((1R,2S)-2-aminocyclohexyl)amino)-5-(pyridin-3-ylamino)-1,2,4-triazine-6-carboxamide. Here, 4-chloro-1-methyl-1H-pyrrolo[2,3-b]pyridine was utilized as the coupling partner instead of 3-bromopyridine. MS found for C18H23N9O as (M+H)+ 382.4. UV: λ=213, 263 nm. Proton NMR: (CD3OD) δ 8.78 (1H, br), 8.28 (1H, br) 7.46 (1H, d, J=3.6 Hz), 6.76 (1H, m), 4.82 (1H, m), 3.93 (3H, s), 3.73 (1H, br), 2.01-1.60 (8H, m) ppm.

Provenance & Evidence