HRID577697

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4770990

1H-Pyrazol-4-amine, 1-methyl-

C4H7N3

结构：CC(C)(C)OC(=O)/N=C(/NC(=O)OC(C)(C)C)n1cccn1

HCID6383521

tert-Butyl [(Z)-[(tert-butoxycarbonyl)amino](1H-pyrazol-1-yl)methylidene]carbamate

C14H22N4O4

PRODUCTS

生成物

$结构：Cn1cc(N/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cn1$

HCID178481025

未命名化合物

收率 92.1%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

1-methyl-1H-pyrazol-4-amine (11.7 g, 0.12 mol) was added portion-wise to a solution of di-tert-butyl [(Z)-1H-pyrazol-1-ylmethylylidene]biscarbamate (17.5 g, 0.056 mol) in MeCN (100 mL). The mixture was stirred for 20 hrs then filtered to afford the title compound (17.5 g, 91% yield) as a crude solid which was used as is in the next step.

WORKUP

后处理

filtrationthen filtered