HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → N-(2,5-dimethylpyrazol-3-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1,3-Dimethyl-1H-pyrazol-5-amine | HCID 520721 | — |
| Product | N-(2,5-dimethylpyrazol-3-yl)acetamide | HCID 574162 | 100% |
Reaction Steps
Pyridine (7.1 mL, 90 mmol) was added to a solution of 2,5-dimethyl-2H-pyrazol-3-ylamine (10 g, 90 mmol) in acetic anhydride (46 mL) at 0° C. and the resulting mixture was stirred at room temperature for 30 min. The solvent was removed under vacuum to yield the title compound as a brownish liquid (13.7 g), yield: 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040558B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-1896fac15466418ea344d06333fbaa35 |
| Source note | uspto-grants-2015_05 |