HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577979Generated: October 30, 2026
Propylene Oxide → HCID 67358844, compound
https://huagongshe.com/reaction/577979
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Propylene Oxide | HCID 6378 | — |
| Reactant | 1-[(Phenylmethyl)amino]-2-butanol | HCID 13163458 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67358844 | HCID 67358844 | — |
Reaction Steps
To a solution of 1-benzylamino-butan-2-ol (Intermediate 482, 8.5 g, 47.48 mmol) in ethanol (150 mL) was added propylene oxide (8.8 g, 151 mmole) and the mixture was heated at 150° C. for 2 h in autoclave. After concentration of the mixture under reduced pressure, the residue was purified by column chromatography using methanol in dichloromethane to give product as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09040528B2 |
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| Source dataset | uspto-grants-2015_05 |
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| ORD ID | ord-68bb673bb5294cd8b4fc0b81a29fe82e |
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| Source note | uspto-grants-2015_05 |
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