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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 577994Generated: October 28, 2026

trans-2,6-Dimethylmorpholine → 6-((2R,6R)-2,6-dimethylmorpholino)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde

https://huagongshe.com/reaction/577994

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttrans-2,6-DimethylmorpholineHCID 11137133—
ReactantHCID 86658113HCID 86658113—
Product6-((2R,6R)-2,6-dimethylmorpholino)-7-fluoro-3-methylbenzo[d]isoxazole-5-carbaldehydeHCID 86658123—

Reaction Steps

Starting materials: 6,7-difluoro-3-methylbenzo[d]isoxazole-5-carbaldehyde (Intermediate 374) and (2R,6R)-2,6-dimethylmorpholine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040528B2
Source datasetuspto-grants-2015_05
ORD IDord-6947d48bd9794d08bde4867668ae13ff
Source noteuspto-grants-2015_05