Tetrahydrofuran → HCID 67233330, compound

Participants

Reaction Steps

Platinum on charcoal (100 mg 5%) was added to the product obtained at (659b) (160 mg, 0.45 mmol) in 10 mL methanol with 5 mL THF and the mixture was hydrogenated at 4 bar H2 pressure at ambient temperature for 5 h. The mixture was filtered, washed with methanol and the filtrate concentrated i. vac. The product was reacted without further purification.

Provenance & Evidence