HCID 67232037, compound → HCID 67233101, compound

HRID 578070Notes

Reaction equation

HRID 578070 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:14]=[C:13]([NH:15]CC2C=CC=CC=2)[C:12]([N+:23]([O-])=O)=[CH:11][C:7]=1[C:8]([OH:10])=[O:9]>[Pd].C1COCC1.CO>[CH3:1][O:2][CH2:3][CH2:4][O:5][C:6]1[CH:14]=[C:13]([NH2:15])[C:12]([NH2:23])=[CH:11][C:7]=1[C:8]([OH:10])=[O:9]

Participants

5

Reactant 1

HCID 67232037HCID 67232037, compound

Product 1

HCID 67233101HCID 67233101, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 655d by hydrogenation of the product obtained from (685a) using palladium on charcoal in THF and methanol.

Workup

  1. customPrepared analogously to example 655d by hydrogenation of the product

Sources & evidence

ORD record
ord-c7b15e5eefba4897a04f706f9f5276c1
Source dataset
uspto-grants-2015_05
Patent number
US09040565B2

Reaction notes

Loading…