HCID 86665219, compound → HCID 86665218, compound

HRID 578071Notes

Reaction equation

HRID 578071 reaction equation
[CH2:1]([O:3][C:4](=[O:28])[C:5]1[CH:10]=[C:9]([N+:11]([O-])=O)[C:8]([NH:14]CC2C=CC=CC=2)=[CH:7][C:6]=1[O:22][CH2:23][CH2:24][N:25]([CH3:27])[CH3:26])[CH3:2]>[Pd].C1COCC1.CO>[CH2:1]([O:3][C:4](=[O:28])[C:5]1[CH:10]=[C:9]([NH2:11])[C:8]([NH2:14])=[CH:7][C:6]=1[O:22][CH2:23][CH2:24][N:25]([CH3:27])[CH3:26])[CH3:2]

Participants

5

Reactant 1

HCID 86665219HCID 86665219, compound

Product 1

HCID 86665218HCID 86665218, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 655d by hydrogenation of the product obtained from (687a) using palladium on charcoal in THF and methanol.

Workup

  1. customPrepared analogously to example 655d by hydrogenation of the product

Sources & evidence

ORD record
ord-03d82e0388d840e8b28b95d941260e6b
Source dataset
uspto-grants-2015_05
Patent number
US09040565B2

Reaction notes

Loading…