Ammonia → HCID 695751, compound

HRID 578103Notes

Reaction equation

HRID 578103 reaction equation
[OH:1][N:2]=[C:3]([NH2:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[Cl:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][C:20]=1[Cl:21])[C:15](O)=O.N>>[Cl:11][C:12]1[CH:13]=[C:14]([C:15]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=3)[N:10]=2)[CH:18]=[CH:19][C:20]=1[Cl:21]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 58173,4-Dichlorobenzoic acidHCID 308113N-Hydroxynicotinimidamide

Product 1

HCID 695751HCID 695751, compound

Procedure

The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 3,4-dichlorobenzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.64 (ddd, J=8.0, 5.1, 0.8 Hz, 1H), 7.82 (d, J=8.3 Hz, 1H), 8.14-8.19 (m, 1H), 8.40 (d, J=2.0 Hz, 1H), 8.56 (dt, J=7.9, 2.0 Hz, 1H), 8.75 (dd, J=5.2, 1.6 Hz, 1H), 9.29 (dd, J=2.2, 1.0 Hz, 1H) ppm; MS (DCI/NH3) m/z 292 (M+H)+.

Sources & evidence

ORD record
ord-e558e50695f04788a76b0f7d94c19822
Source dataset
uspto-grants-2015_05
Patent number
US09040568B2

Reaction notes

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