1,4-Diazepan-6-ol → 1-(6-(6-(5-ethylpyridin-3-yl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyridin-2-yl)-1,4-diazepan-6-ol

Participants

Role	Name	HCID	Charge
Reactant	1,4-Diazepan-6-ol	HCID 21114275	—
Reactant	6-(5-ethylpyridin-3-yl)-1-(6-fluoropyridin-2-yl)-1H-pyrazolo[4,3-c]pyridine	HCID 86707018	—
Product	1-(6-(6-(5-ethylpyridin-3-yl)-1H-pyrazolo[4,3-c]pyridin-1-yl)pyridin-2-yl)-1,4-diazepan-6-ol	HCID 72715046	12%

Reaction Steps

Following the procedures as described in EXAMPLE 8 and starting with 6-(5-ethylpyridin-3-yl)-1-(6-fluoropyridin-2-yl)-1H-pyrazolo[4,3-c]pyridine and 1,4-diazepan-6-ol, 106 was obtained as an off-white solid (49.4 mg, 12%). MS (ESI) m/z: 416.1 [M+H]+

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09434725B2
Source dataset	uspto-grants-2016_09
ORD ID	ord-52908b37ccd9450c8a307710dde7efcd
Source note	uspto-grants-2016_09