HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178513606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 178452326 | HCID 178452326 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178513606 | HCID 178513606 | — |
Reaction Steps
55 mg (0.56 mmol 4-(3-(8-Carbamoyl-quinazolin-4-ylamino)-3-{3-[(5-cyclopropyl-2H-pyrazole-3-carbonyl)-amino]-phenyl}-propyl)-piperazine-1-carboxylic acid tert-butyl ester were dissolved in 1.0 ml dioxane and 350 μl 4 N HCl in dioxane were added. The mixture was stirred overnight, the solid was filtered and washed with dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040560B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-1f3f69c1b1f64ea190721266a8d6e8ba |
| Source note | uspto-grants-2015_05 |