HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzoic Acid → 4-[2-Fluoro-5-(4-methoxy-benzoylamino)-benzylamino]-quinazoline-8-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzoic Acid | HCID 7478 | — |
| Reactant | 5-Amino-2-fluorobenzonitrile | HCID 2737673 | — |
| Reactant | 4-{3-[(4-Methoxy-benzoyl)-methyl-amino]-benzylamino}-quinazoline-8-carboxylic acid amide | HCID 66764075 | — |
| Product | 4-[2-Fluoro-5-(4-methoxy-benzoylamino)-benzylamino]-quinazoline-8-carboxylic acid amide | HCID 66763290 | — |
Reaction Steps
4-[2-Fluoro-5-(4-methoxy-benzoylamino)-benzylamino]-quinazoline-8-carboxylic acid amide was prepared according to example 4-{3-[(4-Methoxy-benzoyl)-methyl-amino]-benzylamino}-quinazoline-8-carboxylic acid amide, starting from 5-Amino-2-fluoro-benzonitrile and 4-methoxy-benzoic acid:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09040560B2 |
| Source dataset | uspto-grants-2015_05 |
| ORD ID | ord-aa36483f51ad438d86e0037c48dad695 |
| Source note | uspto-grants-2015_05 |