2-Fluorophenylboronic acid → HCID 71259057, compound

Participants

Reaction Steps

Subsequently, Suzuki-Miyaura conditions were applied as in FIG. 8 using 2-bromo-5,6,7,8-tetrahydroquinoline and 2-fluorophenylboronic acid to obtain the 2-(2-fluorophenyl)-5,6,7,8-tetrahydroquinoline precursor as depicted in FIG. 10. After isolation and purification by flash chromatography, this viscous yellow-orange liquid solidifies at room temperature. In general, 2-(2-fluorophenyl)-pyridine derivatives wore prepared in high yields (over 92%).

Provenance & Evidence