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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 578826Generated: November 3, 2026

(3-Chlorophenyl)boronic acid → 5-(Bromomethyl)-3-(3-chlorophenyl)-2-(difluoromethoxy)pyridine

https://huagongshe.com/reaction/578826

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Chlorophenyl)boronic acidHCID 2734323—
Reactant3-Bromo-5-(bromomethyl)-2-(difluoromethoxy)pyridineHCID 90414793—
Product5-(Bromomethyl)-3-(3-chlorophenyl)-2-(difluoromethoxy)pyridineHCID 90415856—

Reaction Steps

The title compound was prepared in a manner analogous to Intermediate 10, using Intermediate 4 and 3-chlorophenyl boronic acid in Step 1, followed by bromination according to Step 3. [M+H]=348.17/350.15

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040692B2
Source datasetuspto-grants-2015_05
ORD IDord-da95885dd8054c62bce8ee8f7c6d2ee5
Source noteuspto-grants-2015_05