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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 579027Generated: October 31, 2026

1-(Methoxymethyl)cyclopropan-1-amine hydrochloride → HCID 178494694, compound

https://huagongshe.com/reaction/579027

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Methoxymethyl)cyclopropan-1-amine hydrochlorideHCID 53407230—
ReactantHCID 178487655HCID 178487655—
ProductHCID 178494694HCID 178494694—

Reaction Steps

The title compound was prepared in a manner similar to Example 198 using 6-(5-hydroxy-4-(2-methoxypyridin-4-yl)-1H-pyrazol-1-yl)nicotinic acid and 1-(methoxymethyl)cyclopropanamine hydrochloride. 1H NMR (400 MHz, DMSO-d6) δ ppm 0.80 (s, 4 H) 3.28 (s, 3 H) 3.48 (s, 2 H) 3.90 (s, 3 H) 7.49 (br. s., 1 H) 7.57 (d, J=5.3 Hz, 1 H) 8.08 (d, J=5.6 Hz, 1 H) 8.35-8.50 (m, 2 H) 8.68 (br. s., 1 H) 8.90 (t, J=1.4 Hz, 1 H) 8.98 (s, 1 H). MS m/z 396 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09040522B2
Source datasetuspto-grants-2015_05
ORD IDord-d728a3c00aa1416ea4695ac5dea9cf3e
Source noteuspto-grants-2015_05