N-bromobutanimide → HCID 57668844, compound

HRID 579675Notes

Reaction equation

HRID 579675 reaction equation
C1C(=O)N([Br:8])C(=O)C1.[CH3:9][CH:10]([CH3:25])[CH2:11][N:12]1[C:24]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[C:18]2[C:13]1=[CH:14][CH:15]=[CH:16][CH:17]=2>>[Br:8][C:16]1[CH:15]=[CH:14][C:13]2[N:12]([CH2:11][CH:10]([CH3:25])[CH3:9])[C:24]3[C:19]([C:18]=2[CH:17]=1)=[CH:20][CH:21]=[CH:22][CH:23]=3

Participants

3

Reactant 2

HCID 67184N-bromobutanimideHCID 6620889HCID 6620889, compound

Product 1

HCID 57668844HCID 57668844, compoundYield 84%

Procedure

The procedure for the synthesis of 2 was followed (1 eq. NBS was used) to prepare 3 from 1 as white crystals in an 84% yield. 1H NMR (400 MHz, CDCl3, 298 K): δ(ppm) 8.20-8.19 (d, 1H), 8.05-8.03 (d, 1H), 7.53-7.38 (m, 3H), 7.28-7.21 (m, 2H), 4.04-4.02 (d, 2H), 2.32-2.30 (m, 1H), 0.97-0.94 (d, 6H).

Workup

  1. customThe procedure for the synthesis of 2

Sources & evidence

ORD record
ord-04b22a9ca0b24473b956b1f5b624d24b
Source dataset
uspto-grants-2015_05
Patent number
US09040718B2

Reaction notes

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