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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 579697Generated: October 31, 2026

Benzenesulfonyl chloride → N-(prop-2-yn-1-yl)benzenesulfonamide

https://huagongshe.com/reaction/579697

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenesulfonyl chlorideHCID 7369—
ReactantPropargylamineHCID 239041—
ProductN-(prop-2-yn-1-yl)benzenesulfonamideHCID 11287036—

Reaction Steps

A benzenesulfonyl chloride derivative of the general formula (2) is reacted with propargylamine to obtain an N-propargylbenzenesulfonamide derivative of the general formula (4). A compound of the general formula (4) is reacted with 2-trifluoromethylbenzoyl halide to synthesize a compound of the general formula (1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04749407
Source datasetuspto-grants-1988_06
ORD IDord-5ea7c4146fe44b4c9299f1461e4f377a
Source noteuspto-grants-1988_06