Acetic Anhydride → HCID 16640801, compound

HRID 579715Notes

Reaction equation

HRID 579715 reaction equation
[CH:1]1[CH:6]=[C:5]([S:7]([OH:10])(=[O:9])=[O:8])[CH:4]=[C:3]([NH2:11])[CH:2]=1.[C:12]([O-])(=[O:14])[CH3:13].[Na+:16].C(OC(=O)C)(=O)C>>[Na+:16].[C:12]([NH:11][C:3]1[CH:4]=[C:5]([S:7]([O-:10])(=[O:8])=[O:9])[CH:6]=[CH:1][CH:2]=1)(=[O:14])[CH3:13]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 84743-Aminobenzenesulfonic acidHCID 517045Sodium Acetate

Product 1

HCID 16640801HCID 16640801, compoundYield 95%

Procedure

Metanilic acid (3-aminobenzenesulfonic acid) in an amount of 37.5 parts, and 18.7 parts of sodium acetate are charged into the kneader and the procedure described and 32 parts of acetic anhydride are added to the reaction mixture. The powdery reaction mass is mixed for one hour and then dried at 85° C. in a stream of air to give a 95% yield of 3-acetylaminobenzenesulfonic acid sodium salt. Liquid chromatography and titration analysis indicated a purity of greater than 97% and the presence of about 0.5% metanilic acid.

Workup

  1. additionThe powdery reaction mass is mixed for one hour
  2. customdried at 85° C. in a stream of air

Sources & evidence

ORD record
ord-10fbb3e93c0c459db346be30c685a976
Source dataset
uspto-grants-1988_06
Patent number
US04749523

Reaction notes

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