Phenyl glycidyl ether → HCID 14646908, compound

HRID 579815Notes

Reaction equation

HRID 579815 reaction equation
[CH2:1]([NH:8][OH:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:10]1([O:16][CH2:17][CH:18]2[O:20][CH2:19]2)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C(O)(C)C>[CH2:1]([N:8]([CH2:19][CH:18]([OH:20])[CH2:17][O:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[OH:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 31217Phenyl glycidyl etherHCID 2794173Benzylhydroxylamine

Product 1

HCID 14646908HCID 14646908, compoundYield 35%

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

The procedure of Example 1 is repeated using 3.5 g of N-benzylhydroxylamine and 6.16 g of phenylglycidyl ether in 50 ml of isopropanol. Purification by liquid chromatography affords the title compound in 35% yield as a colorless oil.

Workup

  1. customPurification by liquid chromatography

Sources & evidence

ORD record
ord-ea46d76c1b464cb1bd74e33e4ea9090a
Source dataset
uspto-grants-1988_06
Patent number
US04749733

Reaction notes

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