Hydrochloric Acid → HCID 14180893, compound

Participants

Reaction Steps

1-[(RS)-1-Hydroxy-2-[(2-methylpropyl)(phenylmethyl)amino]ethyl]-3-methylbutylcarbamic acid, 1,1-dimethylethyl ester, hydrochloride (1.67 g, 4.25 mmol) was dissolved in methanol (50 ml) and hydrochloric acid (1N, 4.25 ml) was added. The solution was stirred under an atmosphere of hydrogen in the presence of palladium hydroxide on carbon catalyst (0.36 g) for two hours. It was filtered through Hyflo and concentrated to dryness in vacuo (1.31 g).

Provenance & Evidence