L-Aspartic Acid → HCID 178484999, compound

Participants

Reaction Steps

A mixture of 0.66 g (0.5 cmole) of aspartic acid and 1.26 g (0.5 cmole) of cimetidine was suspended in 15 ml of dichloromethane. It was stirred for 3 hours at room temperature, filtered, washed with dichloromethane and dried. Weight 1.87 g (yield 97.5%). A stereoscopically homogenous microcrystalline white solid. M.p.: 141°-142° C. In the infra red spectrum the lines at 3200, 3130, 2160, 1620 and 1585 cm-1 are characteristic.

Provenance & Evidence