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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580105Generated: October 30, 2026

Piperidine → Piperidine, 1-(2-phenoxyethyl)-

https://huagongshe.com/reaction/580105

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantPotassium CarbonateHCID 11430—
ReactantBenzene, (2-bromoethoxy)-HCID 68526—
SolventEthanolHCID 702—
ProductPiperidine, 1-(2-phenoxyethyl)-HCID 12016996.4%

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture of 20 g of 2-phenoxyethyl bromide thus obtained, 7.92 g of piperidine and 12.86 g of potassium carbonate was added into 100 ml of ethyl alcohol and stirred for 6 hours at 100° C. The reaction mixture was filtered and condensed under reduced pressure to give 18.4 g of 1-(2-phenoxyethyl)piperidine having a boiling point of 111° C. to 112° C. at 7 mmHg in a yield of 90%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04751302
Source datasetuspto-grants-1988_06
ORD IDord-f91f00d08a8c436c8afd3b84dc37f311
Source noteuspto-grants-1988_06