Hydrochloric Acid → 1-(3-Diethylaminopropyl)-3,5-diaminoindazole trihydrochloride

HRID 580121Notes

Reaction equation

HRID 580121 reaction equation
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([NH2:16])=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1)[CH3:2].[ClH:20].C(OCC)C>C(O)C>[ClH:20].[ClH:20].[ClH:20].[CH2:18]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([NH2:16])=[CH:13][CH:14]=2)[C:9]([NH2:17])=[N:8]1)[CH3:19]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 201358391-[3-(Diethylamino)propyl]-1H-indazole-3,5-diamine

Product 1

HCID 201358381-(3-Diethylaminopropyl)-3,5-diaminoindazole trihydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 15 ml of absolute ethyl alcohol was dissolved 0.6 g of 1-(3-diethylaminopropyl)-3,5-diaminoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. To the solution was added anhydrous diethyl ether to separate crystals. Then the crystals were obtained by filtration and dried to give 1-(3-diethylaminopropyl)-3,5-diaminoindazole trihydrochloride having the following analytical value.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-73d3f8d6ff7c42c7bc0cad46a8f4aa69
Source dataset
uspto-grants-1988_06
Patent number
US04751302

Reaction notes

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