反应详情

In 50 ml of absolute ethyl alcohol was dissolved 3.2 g of the 1-(3-piperidinobutyl)-3-(3-diethylaminopropylamino)-5-chloroindazole, and into the solution was introduced dried hydrogen chloride under cooling with ice. Then to the solution was added anhydrous diethyl ether to separate crystals. The crystals were obtained by filtration and dried to give 1-(3-piperidinobutyl)-3-(3-diethylaminopropylamino)-5-chloroindazole dihydrochloride having the following analytical value.

1. temperatureunder cooling with ice
2. customto separate crystals
3. customThe crystals were obtained by filtration
4. customdried