Hydrochloric Acid → HCID 135583104, compound

HRID 580168Notes

Reaction equation

HRID 580168 reaction equation
[CH2:1]([N:3]([CH2:26][CH3:27])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[C:11]([OH:16])[CH:12]=[CH:13][CH:14]=2)[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:24][CH3:25])[CH2:22][CH3:23])=[N:8]1)[CH3:2].[ClH:28].C(OCC)C>C(O)C>[ClH:28].[ClH:28].[CH2:26]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[C:11]([OH:16])[CH:12]=[CH:13][CH:14]=2)[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25])=[N:8]1)[CH3:27]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 135583105HCID 135583105, compound

Product 1

HCID 135583104HCID 135583104, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 50 ml of absolute ethyl alcohol was dissolved 3.1 g of the 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-4-hydroxyindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Then to the solution was added anhydrous diethyl ether to separate crystals. The crystals were obtained by filtration and dried to give 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-4-hydroxyindazole dihydrochloride having the following analytical value.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThe crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-c8e7e4f5e8dc43608cd6b3c03ef7bdc7
Source dataset
uspto-grants-1988_06
Patent number
US04751302

Reaction notes

Loading…