Hydrochloric Acid → HCID 20135789, compound

HRID 580171Notes

Reaction equation

HRID 580171 reaction equation
[CH2:1]([N:3]([CH2:26][CH3:27])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([I:16])=[CH:13][CH:14]=2)[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:24][CH3:25])[CH2:22][CH3:23])=[N:8]1)[CH3:2].[ClH:28].C(OCC)C>C(O)C>[ClH:28].[ClH:28].[CH2:26]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][N:7]1[C:15]2[C:10](=[CH:11][C:12]([I:16])=[CH:13][CH:14]=2)[C:9]([NH:17][CH2:18][CH2:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25])=[N:8]1)[CH3:27]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 20135790HCID 20135790, compound

Product 1

HCID 20135789HCID 20135789, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 50 ml of absolute ethyl alcohol was dissolved 4.0 g of the 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-5-iodoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Then to the solution was added anhydrous diethyl ether to separate crystals. The crystals were obtained by filtration and dried to give 1-(3-diethylaminopropyl)-3-(3-diethylaminopropylamino)-5-iodoindazole dihydrochloride having the following analytical value.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThe crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-86c0cb0a2afe48dfb3976898f8e8b4df
Source dataset
uspto-grants-1988_06
Patent number
US04751302

Reaction notes

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