Hydrochloric Acid → HCID 20135842, compound

HRID 580185Notes

Reaction equation

HRID 580185 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[NH:13][N:12]=2)[CH2:3][CH2:2]1.[ClH:20].C(OCC)C>C(O)C>[ClH:20].[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[NH:13][N:12]=2)[CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 3065651Indazole, 3-((3-morpholinopropyl)amino)-

Product 1

HCID 20135842HCID 20135842, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 15 ml of absolute ethyl alcohol was dissolved 1.0 g of the 3-(3-morpholinopropylamino)indazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. Then to the solution was added anhydrous diethyl ether to separate crystals. The crystals were obtained by filtration and dried to give 3-(3-morpholinopropylamino)indazole hydrochloride having the following analytical value.

Workup

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThe crystals were obtained by filtration
  4. customdried

Sources & evidence

ORD record
ord-b390ca5c4ea74457b3c9eacb66a1a633
Source dataset
uspto-grants-1988_06
Patent number
US04751302

Reaction notes

Loading…