HCID 53640724, compound → HCID 54172645, compound

HRID 580220Notes

Reaction equation

HRID 580220 reaction equation
C(OC([NH:8][C:9]1[S:13][N:12]=[C:11]([C:14](=[N:18][O:19][CH2:20][CH:21]=[CH2:22])[C:15]([OH:17])=[O:16])[N:10]=1)=O)(C)(C)C>FC(F)(F)C(O)=O>[NH2:8][C:9]1[S:13][N:12]=[C:11]([C:14](=[N:18][O:19][CH2:20][CH:21]=[CH2:22])[C:15]([OH:17])=[O:16])[N:10]=1

Participants

3

Reactant 1

HCID 53640724HCID 53640724, compound

Product 1

HCID 54172645HCID 54172645, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

A solution of 570 mg (1.74 mmoles) of 2-(5-t-butoxycarbonylamino-1,2,4-thiadiazol-3-yl)-2-(propen-3-yloxyimino)acetic acid in 6 ml of trifluoroacetic acid was allowed to stand for 1 hour at ambient temperature. Evaporation followed by trituration with 30 ml of isopropyl ether gave 376 mg (95%) of the title compound. Mp. 109° C. (dec.).

Workup

  1. customEvaporation

Sources & evidence

ORD record
ord-aaa2f67c89e34b58bc64ac528499251c
Source dataset
uspto-grants-1988_06
Patent number
US04751295

Reaction notes

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